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Use Caution/Observe. Ethinyl estradiol may possibly inhibit the clearance of benzodiazepines that endure oxidation, thus raising serum concentrations of concomitantly administered benzodiazepines.larotrectinib will enhance the level or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Potent or average